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Thursday, March 7, 2013

Phen-fen

In a nation obsessed with weight red nothing has ever been anything quite like Fen-Phen. It was set of magic pills from the wizards of Big Pharma (Frankel, 2005). The do drugs was a prescription cocktail that promised to curb appetence and promote weight loss easily and safely.
Fen-Phen was an anti-obesity practice of medicine (an anorectic) which consisted of two drugs: fenfluramine and phentermine. Fenfluramine came to the U.S. market in 1973 as a drug made to increase the levels of serotonin depressing the nervous musical arrangement and helping to moderate mood and appetite. Phentermine was introduced in 1959 as an appetite suppressant for those facing an increased medical risk as a result of their weight. This drug has been linked to a matter of side effects and is currently available for prescription in the United States (Aylstock, 2009). Separately, the weight loss results were not dramatic, but together the two drugs produced what was considered to be remarkable results. One study in 1992 claimed that 121 obese patients being treated with Fen-Phen lost an average of xxx pounds apiece. It has been estimated that in 1996 six million Americans took Fen-Phen to treat weight problems, and that in the same year approximately 18 million prescriptions for Fen-Phen were indite (Fen-Phen Diet Drugs Class Action).

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Dexfenfluramine is manufactured for Interneuron Pharmaceuticals and marketed under the name of revived by Wyeth-Ayerst Laboratories, a subsidiary of American Home Products Corp. of Madison, N.J., which similarly manufactures and markets fenfluramine under the brand name Pondimin. The FDA did not request the breakup of phentermine, the third widely used medication for obesity (Bachorik, 1997).
Fen-Phen, was believed to construct the serotonin 2C receptor, causing people to feel full, and eat less. Unfortunately, Fen-Phen to a fault ended up stimulating the serotonin 2B receptor, which eventually direct to the problems with the heart (Madrigal, 2008). In September 1997 the...If you want to get a full essay, order it on our website: Orderessay



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